In this tag team adventure game, switch Eds on the fly to take advantage of their unique abilities. You'll encounter all of your favorite characters from the show as you make your way through the cul-de-sac, scamming the neighborhood kids! Collect Jawbreakers and coins to unlock bonus content.

The game follows the Eds through eight levels, referred to as scams, two of which are unlockable via gameplay and using each Ed's special formations and abilities. In between scams, the Eds are free to roam the Cul-de-sac before heading to the next scam marker. Scams can also be replayed infinitely once they are completed. Eddy can use the El Mongo Stink Bomb, vandalize objects, and swat things with his yo-yo. His formation is the Tower-of-Eddy which can retrieve items high up and traverse narrow beams. Edd can use his sling-shot, operate machines, and smack things with his ruler. His formation is the Trampol-Edd to climb onto high areas and smash pinatas at one time. Ed can "smash stuff" with his head, pick things up and throw them, and dig in sandboxes. His formation is the Batter-Ed which can smash through things as a sort of high speed battering ram.

Ed, Edd n Eddy - The Mis-Edventures is a video game based on Ed, Edd n Eddy. It was released in October 2005 on PC, Xbox, PlayStation 2, Nintendo GameCube, and Game Boy Advance.