A crossover versus fighting game that features characters from both Capcom's video game franchises and comic book series published by Marvel Comics. It is the fifth installment of the Marvel vs. Capcom franchise and the first to use three-dimensional character models instead of sprites.

Players can select a team of three characters to engage in combat and attempt to knock out their opponents. It features similar tag team game mechanics to earlier games in the series, along with new methods of play designed to make the game more accessible to new players. The game was produced by Ryota Niitsuma, who had previously worked on Tatsunoko vs. Capcom: Ultimate All-Stars, which utilizes the same simplified three-button attack system.

The game received generally positive reviews from critics, who praised its gameplay and character roster, while criticizing its online component and lack of features and game modes. More than 2 million units were shipped worldwide a month after its debut, rendering it a commercial success. Less than a year after its release, Capcom announced an updated version of the game, titled Ultimate Marvel vs. Capcom 3, featuring additional characters, stages, and gameplay tweaks.